Phase 2 trial of everolimus and carboplatin combination in patients with triple negative metastatic breast cancer

INTRODUCTION: Rapamycin acts synergistically with platinum agents to induce apoptosis and inhibit proliferation in breast cancer cell lines. Combination of everolimus also known as RAD001 (oral mammalian target of rapamycin (mTOR) inhibitor) and carboplatin may have activity in metastatic triple-neg...

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Detalhes bibliográficos
Main Authors: Singh, Jasmeet Chadha, Novik, Yelena, Stein, Stacey, Volm, Matthew, Meyers, Marlene, Smith, Julia, Omene, Coral, Speyer, James, Schneider, Robert, Jhaveri, Komal, Formenti, Silvia, Kyriakou, Victoria, Joseph, Benson, Goldberg, Judith D, Li, Xiaochun, Adams, Sylvia, Tiersten, Amy
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053575/
https://ncbi.nlm.nih.gov/pubmed/24684785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3634
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