Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome

In this Phase 2 study, we evaluated the efficacy of combination of 5-azacitidine (AZA), valproic acid (VPA), and all-trans retinoic acid (ATRA) in patients with high-risk acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Treatment consisted of six cycles of AZA and VPA for 7 days, foll...

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Detalhes bibliográficos
Main Authors: Raffoux, Emmanuel, Cras, Audrey, Recher, Christian, Boëlle, Pierre-Yves, de Labarthe, Adrienne, Turlure, Pascal, Marolleau, Jean-Pierre, Reman, Oumedaly, Gardin, Claude, Victor, Maud, Maury, Sébastien, Rousselot, Philippe, Malfuson, Jean-Valère, Maarek, Odile, Daniel, Marie-Thérèse, Fenaux, Pierre, Degos, Laurent, Chomienne, Christine, Chevret, Sylvie, Dombret, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053545/
https://ncbi.nlm.nih.gov/pubmed/21293051
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