Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort

DNA methylation is an epigenetic mechanism that regulates gene expression and can be modified by one-carbon nutrients. The objective of this study was to investigate the impact of folic acid (FA) fortification of the US food supply on leukocyte global DNA methylation and the relationship between DNA...

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Detalhes bibliográficos
Main Authors: Bae, Sajin, Ulrich, Cornelia M, Bailey, Lynn B, Malysheva, Olga, Brown, Elissa C, Maneval, David R, Neuhouser, Marian L, Cheng, Ting-Yuan David, Miller, Joshua W, Zheng, Yingye, Xiao, Liren, Hou, Lifang, Song, Xiaoling, Buck, Katharina, Beresford, Shirley AA, Caudill, Marie A
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053458/
https://ncbi.nlm.nih.gov/pubmed/24300587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27323
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