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Prostaglandin E(2) Promotes Features of Replicative Senescence in Chronically Activated Human CD8+ T Cells
Prostaglandin E(2) (PGE(2)), a pleiotropic immunomodulatory molecule, and its free radical catalyzed isoform, iso-PGE(2), are frequently elevated in the context of cancer and chronic infection. Previous studies have documented the effects of PGE(2) on the various CD4+ T cell functions, but little is...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053423/ https://ncbi.nlm.nih.gov/pubmed/24918932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099432 |
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