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Endocrine therapy: defining the path of least resistance

One of the best-characterized oncogenic mechanisms in breast cancer is the aberrant activation of phosphatidylinositol-3-kinase, protein kinase B, and mammalian target of rapamycin signaling. In both endocrine-resistant disease and breast cancer stem cells, this is commonly caused by specific geneti...

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Dades bibliogràfiques
Autors principals: Stone, Andrew, Musgrove, Elizabeth A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053240/
https://ncbi.nlm.nih.gov/pubmed/25928145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3659
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