A methodology to ensure and improve accuracy of Ki67 labelling index estimation by automated digital image analysis in breast cancer tissue

INTRODUCTION: Immunohistochemical Ki67 labelling index (Ki67 LI) reflects proliferative activity and is a potential prognostic/predictive marker of breast cancer. However, its clinical utility is hindered by the lack of standardized measurement methodologies. Besides tissue heterogeneity aspects, th...

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Bibliographische Detailangaben
Hauptverfasser: Laurinavicius, Arvydas, Plancoulaine, Benoit, Laurinaviciene, Aida, Herlin, Paulette, Meskauskas, Raimundas, Baltrusaityte, Indra, Besusparis, Justinas, Dasevicius, Darius, Elie, Nicolas, Iqbal, Yasir, Bor, Catherine, Ellis, Ian O
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053156/
https://ncbi.nlm.nih.gov/pubmed/24708745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3639
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