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New insights into signalling networks regulating breast cancer stem cells

In a recent paper, Aceto and colleagues report that Src homology 2 domain-containing protein tyrosine phosphatase 2 (Shp2) plays a critical role in maintenance of breast tumour-initiating cells, and they define novel effectors downstream of Shp2 that regulate cellular invasion and self-renewal, incl...

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Detalhes bibliográficos
Main Authors: Swarbrick, Alexander, Daly, Roger J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053095/
https://ncbi.nlm.nih.gov/pubmed/22999218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3209
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