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Immune Regulatory Antibodies: Are They the Next Advance?

During the past decade, new insights into the mechanisms by which T-cell activation and proliferation are regulated have led to the identification of checkpoint proteins that either up- or down-modulate T-cell reactivity. In the presence of active malignancy, pathophysiologic inhibition of T-cell ac...

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Autori principali: Wolchok, Jedd D., Yang, Arvin S., Weber, Jeffrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052949/
https://ncbi.nlm.nih.gov/pubmed/20693841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0b013e3181eb3381
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