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Progesterone blunts vascular endothelial cell secretion of endothelin-1 in response to placental ischemia
OBJECTIVE: Preeclampsia (PE) is associated with hypertension and elevated endothelin (ET-1), an indicator of endothelial cell activation and dysfunction. Reduction of uteroplacental perfusion (RUPP) in the pregnant rat model of PE is characterized by elevated mean arterial pressure, inflammatory cyt...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052216/ https://ncbi.nlm.nih.gov/pubmed/23545163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2013.03.032 |
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