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Leptin Alters Adrenal Responsiveness by Decreasing Expression of ACTH-R, StAR, and P450c21 in Hypoxemic Fetal Sheep

The late gestation increase in adrenal responsiveness to adrenocorticotropin (ACTH) is dependent upon the upregulation of the ACTH receptor (ACTH-R), steroidogenic acute regulatory protein (StAR), and steroidogenic enzymes in the fetal adrenal. Long-term hypoxia decreases the expression of these and...

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Detalhes bibliográficos
Main Authors: Su, Yixin, Carey, Luke C., Rose, James C., Pulgar, Victor M.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052208/
https://ncbi.nlm.nih.gov/pubmed/22534336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719112442246
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