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Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells

Our understanding of the intrinsic mechanosensitive properties of human pluripotent stem cells (hPSCs), in particular the effects that the physical microenvironment has on their differentiation, remains elusive(1). Here, we show that neural induction and caudalization of hPSCs can be accelerated by...

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Detalhes bibliográficos
Main Authors: Sun, Yubing, Yong, Koh Meng Aw, Villa-Diaz, Luis G., Zhang, Xiaoli, Chen, Weiqiang, Philson, Renee, Weng, Shinuo, Xu, Haoxing, Krebsbach, Paul H., Fu, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051885/
https://ncbi.nlm.nih.gov/pubmed/24728461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3945
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