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Overexpression of Abl2 predicts poor prognosis in hepatocellular carcinomas and is associated with cancer cell migration and invasion

INTRODUCTION: Abl2 nonreceptor tyrosine kinase (Arg, c-abl oncogene 2) has recently been identified as being recurrently amplified at DNA levels and overexpressed at mRNA levels in hepatocellular carcinomas (HCCs), and might be a potential oncogenic driver and therapeutic target for HCC. METHODS: In...

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Autors principals: Xing, Quan-tai, Qu, Chun-mei, Wang, Gang
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051810/
https://ncbi.nlm.nih.gov/pubmed/24940071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S62348
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