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Generation and Characterisation of a Canine EGFP-HMGA2 Prostate Cancer In Vitro Model

The architectural transcription factor HMGA2 is abundantly expressed during embryonic development. In several malignant neoplasias including prostate cancer, high re-expression of HMGA2 is correlated with malignancy and poor prognosis. The let-7 miRNA family is described to regulate HMGA2 negatively...

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Detalhes bibliográficos
Main Authors: Willenbrock, Saskia, Wagner, Siegfried, Reimann-Berg, Nicola, Moulay, Mohammed, Hewicker-Trautwein, Marion, Nolte, Ingo, Escobar, Hugo Murua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051699/
https://ncbi.nlm.nih.gov/pubmed/24914948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098788
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