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Intraluminal Administration of Poly I:C Causes an Enteropathy That Is Exacerbated by Administration of Oral Dietary Antigen

Systemic administration of polyinosinic:polycytidylic acid (poly I:C), mimics virally-induced activation of TLR3 signalling causing acute small intestine damage, but whether and how mucosal administration of poly I:C causes enteropathy is less clear. Our aim was to investigate the inflammatory pathw...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Araya, Romina E., Jury, Jennifer, Bondar, Constanza, Verdu, Elena F., Chirdo, Fernando G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051664/
https://ncbi.nlm.nih.gov/pubmed/24915573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099236
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