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Two Adjacent and Similar TetR Family Transcriptional Regulator Genes, SAV577 and SAV576, Co-Regulate Avermectin Production in Streptomyces avermitilis

Streptomyces avermitilis is an important bacterial species used for industrial production of avermectins, a family of broad-spectrum anthelmintic agents. We previously identified the protein SAV576, a TetR family transcriptional regulator (TFR), as a downregulator of avermectin biosynthesis that act...

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Bibliographische Detailangaben
Hauptverfasser: Guo, Jia, Zhang, Xuan, Chen, Zhi, Wen, Ying, Li, Jilun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051647/
https://ncbi.nlm.nih.gov/pubmed/24915523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099224
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