Crystallization and preliminary X-ray diffraction analysis of (R)-carbonyl reductase from Candida parapsilosis

The NADH-dependent (R)-carbonyl reductase from Candida parapsilosis (RCR) catalyzes the asymmetric reduction of 2-hydroxyacetophenone (HAP) to produce (R)-1-phenyl-1,2-ethanediol [(R)-PED], which is used as a versatile building block for the synthesis of pharmaceuticals and fine chemicals. To gain i...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Shanshan, Nie, Yao, Yan, Xu, Ko, Tzu-Ping, Huang, Chun-Hsiang, Chan, Hsiu-Chien, Guo, Rey-Ting, Xiao, Rong
Format: Artigo
Sprache:Inglês
Veröffentlicht: International Union of Crystallography 2014
Schlagworte:
Crystallization Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051541/
https://ncbi.nlm.nih.gov/pubmed/24915097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1400908X
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