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In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27
The DNA of several pathogens is very rich in AT base pairs. Typical examples include the malaria parasite Plasmodium falciparum and the causative agents of trichomoniasis and trypanosomiases. This fact has prompted studies of drugs which interact with the minor groove of DNA, some of which are used...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
International Union of Crystallography
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051503/ https://ncbi.nlm.nih.gov/pubmed/24914972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S139900471400697X |
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