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The differentiation effect of low-dose cytosine arabinoside is disturbed in PU.1-knockdown K562 cells

We recently demonstrated by using PU.1-knockdown K562 (K562 PU.1KD) cells stably expressing PU.1 short inhibitory RNAs and PU.1-overexpressing K562 (K562 PU.1OE) cells, that therapeutic concentrations of 5-aza-2′-deoxycytidine (5-azadC) induce erythroid differentiation of these cells and that the PU...

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Bibliografske podrobnosti
Main Authors: NAKANO, HIROKO, YANAGITA, AKANE, TAKAHASHI, SHINICHIRO
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051488/
https://ncbi.nlm.nih.gov/pubmed/24944809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2014.265
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