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Tissue Kallikrein-Modified Human Endothelial Progenitor Cell Implantation Improves Cardiac Function via Enhanced Activation of Akt and Increased Angiogenesis

Endothelial progenitor cells (EPCs) have been shown to enhance angiogenesis not only by incorporating into the vasculature but also by secreting cytokines, thereby serving as an ideal vehicle for gene transfer. As tissue kallikrein (TK) has pleiotropic effects in inhibiting apoptosis and oxidative s...

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Detalhes bibliográficos
Main Authors: Yao, Yuyu, Sheng, Zulong, Li, Yefei, Fu, Cong, Ma, Genshan, Liu, Naifeng, Chao, Julie, Chao, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051305/
https://ncbi.nlm.nih.gov/pubmed/23508045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2013.48
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