Dual targeting of integrin α(v)β(3) and matrix metalloproteinase-2 for optical imaging of tumors and chemotherapeutic delivery

Activatable cell penetrating peptides (ACPPs) provide a general strategy for molecular targeting by exploiting the extracellular protease activities associated with disease. Previous work used a matrix metalloproteinase (MMP-2 and 9) cleavable sequence in the ACPP to target contrast agents for tumor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Crisp, Jessica L., Savariar, Elamprakash N., Glasgow, Heather L., Ellies, Lesley G., Whitney, Michael A., Tsien, Roger. Y.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051287/
https://ncbi.nlm.nih.gov/pubmed/24737028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-1067
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