Experimental Validation of Multi-Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins

Leishmaniasis is a significant worldwide health problem for which no vaccine exists. Activation of CD4(+) and CD8(+) T cells is crucial for the generation of protective immunity against parasite. Recent trend in vaccine design has been shifted to epitope-based vaccines that are more specific, safe,...

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Hlavní autoři: Agallou, Maria, Athanasiou, Evita, Koutsoni, Olga, Dotsika, Eleni, Karagouni, Evdokia
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051127/
https://ncbi.nlm.nih.gov/pubmed/24959167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00268
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