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Fluid shear stress threshold regulates angiogenic sprouting

The density and architecture of capillary beds that form within a tissue depend on many factors, including local metabolic demand and blood flow. Here, using microfluidic control of local fluid mechanics, we show the existence of a previously unappreciated flow-induced shear stress threshold that tr...

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Détails bibliographiques
Auteurs principaux: Galie, Peter A., Nguyen, Duc-Huy T., Choi, Colin K., Cohen, Daniel M., Janmey, Paul A., Chen, Christopher S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050561/
https://ncbi.nlm.nih.gov/pubmed/24843171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310842111
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