X Chromosome of Female Cells Shows Dynamic Changes in Status during Human Somatic Cell Reprogramming

Induced pluripotent stem cells (iPSCs) acquire embryonic stem cell (ESC)-like epigenetic states, including the X chromosome. Previous studies reported that human iPSCs retain the inactive X chromosome of parental cells, or acquire two active X chromosomes through reprogramming. Most studies investig...

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Autori principali: Kim, Kun-Yong, Hysolli, Eriona, Tanaka, Yoshiaki, Wang, Brandon, Jung, Yong-Wook, Pan, Xinghua, Weissman, Sherman Morton, Park, In-Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050354/
https://ncbi.nlm.nih.gov/pubmed/24936474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.04.003
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