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Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood–brain barrier dysfunction

HIV-1 genetic differences influence viral replication and progression to AIDS. HIV-1 circulating recombinant form (CRF)02_AG is the predominant viral subtype infecting humans in West and Central Africa, but its effects on HIV neuropathogenesis are not known. In the present study, we investigated the...

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Detalhes bibliográficos
Main Authors: Woollard, Shawna M, Bhargavan, Biju, Yu, Fang, Kanmogne, Georgette D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050250/
https://ncbi.nlm.nih.gov/pubmed/24667918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.54
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