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Contribution of genetic polymorphisms on functional status at very old age: A gene-based analysis of 38 genes (311 SNPs) in the oxidative stress pathway

Preservation of functional ability is a well-recognized marker of longevity. At a molecular level, a major determinant of the physiological decline occurring with aging is the imbalance between production and accumulation of oxidative damage to macromolecules, together with a decreased efficiency of...

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Autors principals: Dato, S., Soerensen, M., Lagani, V., Montesanto, A., Passarino, G., Christensen, K., Tan, Q., Christiansen, L.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050201/
https://ncbi.nlm.nih.gov/pubmed/24462499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.01.014
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