Mesenchymal Stem Cells from Human Fat Engineered to Secrete BMP4 are Non-Oncogenic, Suppress Brain Cancer, and Prolong Survival

PURPOSE: Glioblastoma (GBM) is the most common adult primary malignant intracranial cancer. It is associated with poor outcomes due to its invasiveness and resistance to multimodal therapies. Human adipose-derived mesenchymal stem cells (hAMSCs) are a potential treatment because of their tumor tropi...

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Bibliografiska uppgifter
Huvudupphovsmän: Li, Qian, Wijesekera, Olindi, Salas, Sussan J., Wang, Joanna Y., Zhu, Mingxin, Aprhys, Colette, Chaichana, Kaisorn L., Chesler, David A., Zhang, Hao, Smith, Christopher L., Guerrero-Cazares, Hugo, Levchenko, Andre, Quinones-Hinojosa, Alfredo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050066/
https://ncbi.nlm.nih.gov/pubmed/24789034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1415
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