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An Improved Model of Heat-Induced Hyperalgesia—Repetitive Phasic Heat Pain Causing Primary Hyperalgesia to Heat and Secondary Hyperalgesia to Pinprick and Light Touch

This study tested a modified experimental model of heat-induced hyperalgesia, which improves the efficacy to induce primary and secondary hyperalgesia and the efficacy-to-safety ratio reducing the risk of tissue damage seen in other heat pain models. Quantitative sensory testing was done in eighteen...

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Detalhes bibliográficos
Main Authors: Jürgens, Tim P., Sawatzki, Alexander, Henrich, Florian, Magerl, Walter, May, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050052/
https://ncbi.nlm.nih.gov/pubmed/24911787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099507
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