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Are genes switched on when they kiss?
Chromatin loops are pervasive and permit the tight compaction of DNA within the confined space of the nucleus. Looping enables distal genes and DNA elements to engage in chromosomal contact, to form multigene complexes. Advances in biochemical and imaging techniques reveal that loop-mediated contact...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4049915/ https://ncbi.nlm.nih.gov/pubmed/24637837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.28352 |
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