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A rapidly evolving genomic toolkit for Drosophila heterochromatin

Heterochromatin is the enigmatic eukaryotic genome compartment found mostly at telomeres and centromeres. Conventional approaches to sequence assembly and genetic manipulation fail in this highly repetitive, gene-sparse, and recombinationally silent DNA. In contrast, genetic and molecular analyses o...

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Bibliografiske detaljer
Main Authors: Levine, Mia T, Malik, Harmit S
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049844/
https://ncbi.nlm.nih.gov/pubmed/23519206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/fly.24335
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