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Cell-Mediated Degradation Regulates Human Mesenchymal Stem Cell Chondrogenesis and Hypertrophy in MMP-Sensitive Hyaluronic Acid Hydrogels

Photocrosslinked methacrylated hyaluronic acid (MeHA) hydrogels support chondrogenesis of encapsulated human mesenchymal stem cells (hMSCs). However, the covalent crosslinks formed via chain polymerization in these hydrogels are hydrolytically non-degradable and restrict cartilage matrix spatial dis...

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Hlavní autoři: Feng, Qian, Zhu, Meiling, Wei, Kongchang, Bian, Liming
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049825/
https://ncbi.nlm.nih.gov/pubmed/24911871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099587
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