β,β-Dimethylacrylshikonin sensitizes human colon cancer cells to ionizing radiation through the upregulation of reactive oxygen species

Shikonin, a naphthoquinone derivative, has been shown to possess antitumor activity. In the present study, the effects of shikonin and its analog, β,β-dimethylacrylshikonin, were investigated as radiosensitizers on the human colon cancer cell line, HCT-116. Shikonin and, to a greater extent, its ana...

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Hlavní autoři: KWAK, SEO-YOUNG, JEONG, YOUN KYOUNG, KIM, BU-YEON, LEE, JI YOUNG, AHN, HYUN-JOO, JEONG, JAE-HOON, KIM, MI-SOOK, KIM, JOON, HAN, YOUNG-HOON
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049772/
https://ncbi.nlm.nih.gov/pubmed/24932238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2018
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