A Defective TLR4 Signaling for IFN-β Expression Is Responsible for the Innately Lower Ability of BALB/c Macrophages to Produce NO in Response to LPS as Compared to C57BL/6

C57BL/6 mice macrophages innately produce higher levels of NO than BALB/c cells when stimulated with LPS. Here, we investigated the molecular events that account for this intrinsic differential production of NO. We found that the lower production of NO in BALB/c is not due to a subtraction of L-argi...

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Detalhes bibliográficos
Main Authors: Oliveira, Luciana S., de Queiroz, Nina M. G. P., Veloso, Laura V. S., Moreira, Thaís G., Oliveira, Fernanda S., Carneiro, Matheus B. H., Faria, Ana M., Vieira, Leda Q., Oliveira, Sérgio C., Horta, Maria F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049611/
https://ncbi.nlm.nih.gov/pubmed/24911280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098913
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