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Arsenic trioxide induces oxidative stress, DNA damage, and mitochondrial pathway of apoptosis in human leukemia (HL-60) cells

BACKGROUND: Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML), which accounts for approximately 10% of all acute myloid leukemia cases. It is a blood cancer that is formed by chromosomal mutation. Each year in the United States, APL affects about 1,500 patients of all a...

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Main Authors: Kumar, Sanjay, Yedjou, Clement G, Tchounwou, Paul B
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049373/
https://ncbi.nlm.nih.gov/pubmed/24887205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-33-42
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