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Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death

In this review, we address the following question: Are modifications at the level of sarcomeric proteins in acquired heart failure early inducers of altered cardiac dynamics and signaling leading to remodeling and progression to decompensation? There is no doubt that most inherited cardiomyopathies...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yar, Sumeyye, Monasky, Michelle M., Solaro, R. John
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049313/
https://ncbi.nlm.nih.gov/pubmed/24488009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-014-1457-7
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