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Defects in pancreatic development and glucose metabolism in SMN-depleted mice independent of canonical spinal muscular atrophy neuromuscular pathology

Spinal muscular atrophy (SMA) is characterized by motor neuron loss, caused by mutations or deletions in the ubiquitously expressed survival motor neuron 1 (SMN1) gene. We recently identified a novel role for Smn protein in glucose metabolism and pancreatic development in both an intermediate SMA mo...

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מידע ביבליוגרפי
Main Authors: Bowerman, Melissa, Michalski, John-Paul, Beauvais, Ariane, Murray, Lyndsay M., DeRepentigny, Yves, Kothary, Rashmi
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049303/
https://ncbi.nlm.nih.gov/pubmed/24497575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu052
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