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Treatment of Advanced Pancreatic Carcinoma with (90)Y-Clivatuzumab Tetraxetan: A Phase I Single-Dose Escalation Trial

PURPOSE: Humanized antibody hPAM4 specifically binds a mucin glycoprotein expressed in pancreatic adenocarcinomas. This phase I study evaluated a single dose of (90)Y-clivatuzumab tetraxetan ((90)Y-labeled hPAM4) in patients with advanced pancreatic cancer. EXPERIMENTAL DESIGN: Twenty-one patients (...

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Detalhes bibliográficos
Main Authors: Gulec, Seza A., Cohen, Steven J., Pennington, Kenneth L., Zuckier, Lionel S., Hauke, Ralph J., Horne, Heather, Wegener, William A., Teoh, Nick, Gold, David V., Sharkey, Robert M., Goldenberg, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048986/
https://ncbi.nlm.nih.gov/pubmed/21527562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2579
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