Cardiac Safety Analysis of Doxorubicin and Cyclophosphamide Followed by Paclitaxel With or Without Trastuzumab in the North Central Cancer Treatment Group N9831 Adjuvant Breast Cancer Trial

PURPOSE: To assess cardiac safety and potential cardiac risk factors associated with trastuzumab in the NCCTG N9831 Intergroup adjuvant breast cancer trial. PATIENTS AND METHODS: Patients with HER2-positive operable early breast cancer were randomized to 1 of 3 treatment arms: doxorubicin plus cyclo...

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Detalhes bibliográficos
Main Authors: Perez, Edith A., Suman, Vera J., Davidson, Nancy E., Sledge, George W., Kaufman, Peter A., Hudis, Clifford A., Martino, Silvana, Gralow, Julie R., Dakhil, Shaker R., Ingle, James N., Winer, Eric P., Gelmon, Karen A., Gersh, Bernard J., Jaffe, Allan S., Rodeheffer, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048960/
https://ncbi.nlm.nih.gov/pubmed/18250349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.13.5467
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