Cardiac Safety Analysis of Doxorubicin and Cyclophosphamide Followed by Paclitaxel With or Without Trastuzumab in the North Central Cancer Treatment Group N9831 Adjuvant Breast Cancer Trial

PURPOSE: To assess cardiac safety and potential cardiac risk factors associated with trastuzumab in the NCCTG N9831 Intergroup adjuvant breast cancer trial. PATIENTS AND METHODS: Patients with HER2-positive operable early breast cancer were randomized to 1 of 3 treatment arms: doxorubicin plus cyclo...

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Главные авторы: Perez, Edith A., Suman, Vera J., Davidson, Nancy E., Sledge, George W., Kaufman, Peter A., Hudis, Clifford A., Martino, Silvana, Gralow, Julie R., Dakhil, Shaker R., Ingle, James N., Winer, Eric P., Gelmon, Karen A., Gersh, Bernard J., Jaffe, Allan S., Rodeheffer, Richard J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048960/
https://ncbi.nlm.nih.gov/pubmed/18250349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.13.5467
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