Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor

Eya proteins are transcription factors that play pivotal roles in organ formation during development by mediating interactions between Sine Oculis (SO) and Dachshund (DAC). Remarkably, the transcriptional activity of Eya proteins is regulated by a dephosphorylating activity within its Eya domain (ED...

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Detalhes bibliográficos
Main Authors: Jung, Suk-Kyeong, Jeong, Dae Gwin, Chung, Sang J., Kim, Jae Hoon, Park, Byoung Chul, Tonks, Nicholas K., Ryu, Seong Eon, Kim, Seung Jun
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048942/
https://ncbi.nlm.nih.gov/pubmed/19858093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-143891
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