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IL-17 Contributes to Neutrophil Recruitment but Not to Control of Viral Replication During Acute Mouse Adenovirus Type 1 Respiratory Infection

IL-17-producing CD4(+) helper T cells (Th17 cells) promote inflammatory responses to many pathogens. We used mouse adenovirus type 1 (MAV-1) to determine contributions of IL-17 to adenovirus pathogenesis. MAV-1 infection of C57BL/6 mice upregulated lung expression of IL-17 and the Th17-associated fa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McCarthy, Mary K., Zhu, Lingqiao, Procario, Megan C., Weinberg, Jason B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048921/
https://ncbi.nlm.nih.gov/pubmed/24889245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.04.008
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