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Ceftriaxone, a GLT-1 transporter activator, disrupts hippocampal learning in rats

Glutamate transporters (GluTs) are important for maintaining optimal glutamate concentrations at the synapse. This allows proper synaptic response, plasticity and prevents neurotoxicity. It has been shown that the β-lactam antibiotic ceftriaxone (Rocephin) induces an up-regulation of the glutamate t...

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Autores principales: Matos-Ocasio, Félix, Hernández-López, Anixa, Thompson, Kenira J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048801/
https://ncbi.nlm.nih.gov/pubmed/24650590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2014.03.011
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