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Cardioprotective Signaling by Endothelin

The endothelin axis promotes survival signaling pathways in the heart, inviting the idea to use antagonists of endothelin signaling for the treatment of heart failure. Promising results from animal trials, however, failed to show beneficial effects in heart failure patients. Here we review the role...

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Main Authors: Schorlemmer, Anita, Matter, Michelle L., Shohet, Ralph V.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048746/
https://ncbi.nlm.nih.gov/pubmed/19232951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2008.11.005
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