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Mixed confinement regimes during equilibrium confinement spectroscopy of DNA

We have used a combination of fluorescence microscopy experiments and Pruned Enriched Rosenbluth Method simulations of a discrete wormlike chain model to measure the mean extension and the variance in the mean extension of λ-DNA in 100 nm deep nanochannels with widths ranging from 100 nm to 1000 nm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gupta, Damini, Sheats, Julian, Muralidhar, Abhiram, Miller, Jeremy J., Huang, Derek E., Mahshid, Sara, Dorfman, Kevin D., Reisner, Walter
Format: Artigo
Sprache:Inglês
Veröffentlicht: AIP Publishing LLC 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048444/
https://ncbi.nlm.nih.gov/pubmed/24908035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4879515
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