Pigment epithelium-derived factor expression prolongs survival and enhances the cytotoxicity of low-dose chemotherapy in castration-refractory prostate cancer

There is currently no cure for advanced castration-refractory prostate cancer (CRPC) despite the recent approval of several new therapeutic agents. We report here the anti-tumor effect of the angio-inhibitory pigment epithelium-derived factor (PEDF) in the metastatic LNCaP-derivative CRPC CL1 model...

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Autori principali: Nelius, T, Martinez-Marin, D, Hirsch, J, Miller, B, Rinard, K, Lopez, J, de Riese, W, Filleur, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047872/
https://ncbi.nlm.nih.gov/pubmed/24810046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.180
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