Discovery of Colorectal Cancer Biomarker Candidates by Membrane Proteomic Analysis and Subsequent Verification using Selected Reaction Monitoring (SRM) and Tissue Microarray (TMA) Analysis

Recent advances in quantitative proteomic technology have enabled the large-scale validation of biomarkers. We here performed a quantitative proteomic analysis of membrane fractions from colorectal cancer tissue to discover biomarker candidates, and then extensively validated the candidate proteins...

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Hauptverfasser: Kume, Hideaki, Muraoka, Satoshi, Kuga, Takahisa, Adachi, Jun, Narumi, Ryohei, Watanabe, Shio, Kuwano, Masayoshi, Kodera, Yoshio, Matsushita, Kazuyuki, Fukuoka, Junya, Masuda, Takeshi, Ishihama, Yasushi, Matsubara, Hisahiro, Nomura, Fumio, Tomonaga, Takeshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047467/
https://ncbi.nlm.nih.gov/pubmed/24687888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.037093
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