Cyclin-dependent Kinase 8 Module Expression Profiling Reveals Requirement of Mediator Subunits 12 and 13 for Transcription of Serpent-dependent Innate Immunity Genes in Drosophila

The Cdk8 (cyclin-dependent kinase 8) module of Mediator integrates regulatory cues from transcription factors to RNA polymerase II. It consists of four subunits where Med12 and Med13 link Cdk8 and cyclin C (CycC) to core Mediator. Here we have investigated the contributions of the Cdk8 module subuni...

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Autors principals: Kuuluvainen, Emilia, Hakala, Heini, Havula, Essi, Sahal Estimé, Michelle, Rämet, Mika, Hietakangas, Ville, Mäkelä, Tomi P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047394/
https://ncbi.nlm.nih.gov/pubmed/24778181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541904
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