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Cell Surface Translocation of Annexin A2 Facilitates Glutamate-induced Extracellular Proteolysis

Glutamate-induced elevation in intracellular Ca(2+) has been implicated in excitotoxic cell death. Neurons respond to increased glutamate levels by activating an extracellular proteolytic cascade involving the components of the plasmin-plasminogen system. AnxA2 is a Ca(2+)-dependent phospholipid bin...

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Bibliografski detalji
Glavni autori: Valapala, Mallika, Maji, Sayantan, Borejdo, Julian, Vishwanatha, Jamboor K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047365/
https://ncbi.nlm.nih.gov/pubmed/24742684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.511550
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