Ondansetron reduces naturalistic drinking in non-treatment seeking alcohol dependent individuals with the LL 5′-HTTLPR genotype: a laboratory study

BACKGROUND: One hypothesis suggests that the differential response to ondansetron and serotonin specific re-uptake inhibitors (SSRIs) may be due to a functional polymorphism of the 5′-HTTLPR promoter region in SLC6A4, the gene that codes for the serotonin transporter (5-HTT). The LL 5′-HTTLPR genoty...

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Hauptverfasser: Kenna, George A., Zywiak, William H., Swift, Robert M., McGeary, John E., Clifford, James S., Shoaff, Jessica R., Vuittonet, Cynthia, Fricchione, Samuel, Brickley, Michael, Beaucage, Kayla, Haass-Koffler, Carolina L., Leggio, Lorenzo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047179/
https://ncbi.nlm.nih.gov/pubmed/24773166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12410
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