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Development and Validation of a Bioreactor System for Dynamic Loading and Mechanical Characterization of Whole Human Intervertebral Discs in Organ Culture

Intervertebral disc (IVD) degeneration is a common cause of back pain, and attempts to develop therapies are frustrated by lack of model systems that mimic the human condition. Human IVD organ culture models can address this gap, yet current models are limited since vertebral endplates are removed t...

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Detalhes bibliográficos
Main Authors: Walter, BA, Illien-Junger, S, Nasser, P, Hecht, AC, Iatridis, JC
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047158/
https://ncbi.nlm.nih.gov/pubmed/24725441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2014.03.015
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