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Assessing the incremental predictive performance of novel biomarkers over standard predictors

It is unclear to what extent the incremental predictive performance of a novel biomarker is impacted by the method used to control for standard predictors. We investigated whether adding a biomarker to a model with a published risk score overestimates its incremental performance as compared to addin...

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Bibliographic Details
Main Authors: Xanthakis, Vanessa, Sullivan, Lisa M., Vasan, Ramachandran S., Benjamin, Emelia J., Massaro, Joseph M., D’Agostino, Ralph B., Pencina, Michael J.
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047140/
https://ncbi.nlm.nih.gov/pubmed/24719270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6165
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