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The NOD-Like Receptor Signalling Pathway in Helicobacter pylori Infection and Related Gastric Cancer: A Case-Control Study and Gene Expression Analyses

BACKGROUND: Currently, it is well established that cancer arises in chronically inflamed tissue. A number of NOD-like receptors (NLRs) form inflammasomes, intracellular multiprotein complexes critical for generating mature pro-inflammatory cytokines (IL-1β and IL-18). As chronic inflammation of the...

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Detalhes bibliográficos
Main Authors: Castaño-Rodríguez, Natalia, Kaakoush, Nadeem O., Goh, Khean-Lee, Fock, Kwong Ming, Mitchell, Hazel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047072/
https://ncbi.nlm.nih.gov/pubmed/24901306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098899
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